On Beyond Cancer

My life with metastatic breast cancer

Possibilities for personalized cancer treatment October 25, 2013

Filed under: Uncategorized — onbeyondcancer @ 9:22 am

In searching for more information about the genetic testing Dr. T had recommended I found this article explaining the partnership between the testing company, Foundation Medicine, and the pharmaceutical company, Novartis.

Genomics Goes to (Clinical) Trial

Foundation Medicine will profile tumor genomes for Novartis’ cancer drug trials.

A partnership between pharmaceutical giant Novartis and genomics company Foundation Medicine could bring more cancer therapeutics to the clinic at an accelerated pace.

Novartis plans to use Foundation Medicine’s genome interpretation technology as part of its clinical trial enrollment process for cancer drug testing over the next three years. This type of tumor genome analysis, which involves searching for potential drug targets in the genetic sequence of tumors, is already an important part of Novartis’ clinical trials, reports GenomeWeb.

One of the promises of genomic sequencing and personalized medicine is that drug treatments can be tailored to the genetic anomalies of a patient’s tumor, which may be quite different from those of another patient’s tumor. Novartis could use the genomic profiles of patients’ tumors to better select participants for their clinical trials or perhaps to identify new molecular targets for treatment.

“The comprehensive molecular assessment of Novartis’ Oncology clinical trial samples is expected to help to bring potentially lifesaving therapies to the right patients more quickly, and we expect that the wealth of molecular information will help fundamentally improve the way cancer is understood and treated,” said president and CEO of Foundation Medicine Michael Pellini in a statement.


5 Responses to “Possibilities for personalized cancer treatment”

  1. Leslie Says:

    Hi Karissa, I continue to think of you as I am researching options for my mother. Have you heard of noscapine? It has low toxicity and could have a synergistic effect with Gemzar. The problem is that it is not available in the U.S. I am looking into getting support from her doctors and possibly applying for compassionate use through the FDA. I’ll keep you updated. Here is a link to some research: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216931/#!po=72.9167

    Warm regards, Leslie

    Sent from my iPad


  2. Margie Says:

    Sounds very hopeful! 🙂 Love, Mom

  3. Robin Says:

    Siva was mentioning the idea of genetic testing being an option. Will your insurance cover this?

    • I hope so, at least partially. The test costs $5800. Then depending on the results, we may have trouble getting the recommended treatment covered if its not FDA approved for breast cancer.

  4. Aunt Cindy Says:

    Good Luck!

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